NOTE: This report is compiled on an ongoing basis by MLSsoccer.com editors based on club game notes, news reports, and original reporting. The league does not have an official player availability report.
- OUT: Luis Abram (international duty)
- OUT: Saba Lobjanidze (international duty)
- OUT: Edwin Mosquera (knee)
Austin FC
- OUT: Julio Cascante (international duty)
- OUT: Dani Pereira (international duty)
- OUT: Junior Urso (lower leg)
- QUESTIONABLE: Brandon Cambridge (thigh)
- OUT: Chase Gasper (leg)
- OUT: Andrew Gutman (leg)
- OUT: Federico Navarro (leg)
- OUT: Tobias Salquist (leg)
- OUT: Xherdan Shaqiri (international duty)
- OUT: Corey Baird (hip)
- OUT: Nick Hagglund (leg)
- OUT: Matt Miazga (leg)
- OUT: Malik Pinto (ankle)
- OUT: Miles Robinson (international duty)
Colorado Rapids
- OUT: Moïse Bombito (international duty)
- OUT: Daniel Chacón (knee)
- OUT: Jackson Travis (stress fracture)
- OUT: Evan Bush (arm)
- OUT: Jacen Russell-Rowe (international duty)
FC Dallas
- OUT: Patrickson Delgado (knee)
- OUT: Jesús Ferreira (upper leg)
- OUT: Geovane Jesus (knee)
- OUT: Tsiki Ntsabeleng (illness)
- OUT: Paxton Pomykal (knee)
- OUT: Carl Sainté (lower leg)
- OUT: Alan Velasco (knee)
D.C. United
- OUT: Conner Antley (knee)
- OUT: Steven Birnbaum (hip)
- OUT: Russell Canouse (not due to injury)
- OUT: Kristian Fletcher (ankle)
- OUT: Jackson Hopkins (back)
- OUT: Garrison Tubbs (head)
Houston Dynamo FC
- OUT: Adalberto Carrasquilla (international duty)
- OUT: Nelson Quinones (knee)
- QUESTIONABLE: McKinze Gaines (lower body)
- OUT: Lorenzo Dellavalle (knee)
- OUT: Cristian Olivera (international duty)
- QUESTIONABLE: Luis Müller (hip)
- OUT: Gastón Brugman (knee)
- OUT: Jonathan Perez (hamstring)
Inter Miami CF
- OUT: Facundo FarÃas (knee)
- OUT: Nicolás Freire (knee)
- OUT: Lionel Messi (international duty)
- OUT: MatÃas Rojas (international duty)
- OUT: Luis Suárez (international duty)
- QUESTIONABLE: Diego Gómez (ankle)
- QUESTIONABLE: Federico Redondo (adductor)
- QUESTIONABLE: Marcelo Weigandt (hamstring)
Minnesota United FC
- OUT: Hugo Bacharach (knee)
- OUT: Alejandro Bran (international duty)
- OUT: Franco Fragapane (leg)
- OUT: Carlos Harvey (international duty)
- OUT: Tani Oluwaseyi (international duty)
- OUT: Teemu Pukki (knee)
- OUT: Dayne St. Clair (international duty)
- OUT: Mathieu Choinière (international duty)
- OUT: Ariel Lassiter (international duty)
- OUT: Samuel Piette (international duty)
- OUT: Joel Waterman (international duty)
- QUESTIONABLE: Fernando Alvarez (illness)
- QUESTIONABLE: Mason Toye (lower body)
Nashville SC
- OUT: Julian Gaines (ankle)
- OUT: Anibal Godoy (lower body)
- OUT: Randall Leal (hip)
- OUT: Lukas MacNaughton (ankle)
- OUT: Shaq Moore (international duty)
- OUT: Jacob Shaffelburg (international duty)
- OUT: Tomas Chancalay (knee)
- OUT: Nacho Gil (knee)
- OUT: Henrich Ravas (international duty)
- QUESTIONABLE: Dylan Borrero (hip)
- QUESTIONABLE: Carles Gil (lower leg)
- QUESTIONABLE: Tommy McNamara (hamstring)
- QUESTIONABLE: Peyton Miller (thigh)
- QUESTIONABLE: Ryan Spaulding (hamstring)
- QUESTIONABLE: Bobby Wood (calf)
New York City FC
- OUT: None
New York Red Bulls
- OUT: Carlos Coronel (international duty)
- OUT: Roald Mitchell (knee)
- OUT: Serge Ngoma (knee)
- OUT: Peter Stroud (ankle)
- QUESTIONABLE: Emil Forsberg (foot)
Orlando City SC
- OUT: David Brekalo (international duty)
- OUT: Wilder Cartagena (international duty)
- OUT: Pedro Gallese (international duty)
- OUT: Mikey Halliday (knee)
- OUT: Ramiro Enrique (not due to injury)
- QUESTIONABLE: Felipe Martins (foot)
- QUESTIONABLE: Tahir Reid-Brown (thigh)
Philadelphia Union
- OUT: Alejandro Bedoya (quad)
- OUT: Andre Blake (knee)
- OUT: Isaiah LeFlore (knee)
- OUT: José MartÃnez (international duty)
- OUT: Mikael Uhre (adductor)
- QUESTIONABLE: Markus Anderson (hip)
Portland Timbers
- OUT: Miguel Araujo (international duty)
- OUT: Max Crepeau (international duty)
- OUT: Marvin Loria (lower leg)
- OUT: Kamal Miller (international duty)
Real Salt Lake
- Matchday 23 bye
- OUT: Carlos Akapo (lower body)
- OUT: Daniel (lower body)
- OUT: Carlos Gruezo (international duty)
- OUT: JR Marcinkowski (knee)
- OUT: Jamar Ricketts (lower body)
- OUT: Bruno Wilson (lower body)
- OUT: Jon Bell (international duty)
- OUT: Braudilio Rodrigues (hamstring)
Sporting Kansas City
- OUT: Felipe Hernández (not due to injury)
- OUT: Logan Ndenbe (knee)
- QUESTIONABLE: Robert Castellanos (ankle)
- QUESTIONABLE: Daniel Salloi (ankle)
- QUESTIONABLE: Remi Walter (knee)
- OUT: Rasmus Alm (knee)
- OUT: Kyle Hiebert (international duty)
- OUT: Joakim Nilsson (hamstring)
- OUT: Tomáš Ostrák (ankle)
- OUT: Célio Pompeu (lower leg)
- QUESTIONABLE: Klauss (knee)
- QUESTIONABLE: Tim Parker (groin)
Toronto FC
- OUT: Alonso Coello (thigh)
- OUT: Sean Johnson (international duty)
- OUT: Richie Laryea (international duty)
- OUT: Jonathan Osorio (international duty)
- OUT: Brandon Servania (knee)
- OUT: Tyrese Spicer (low back)
- QUESTIONABLE: Matty Longstaff (knee)
Vancouver Whitecaps FC
- OUT: Sam Adekugbe (calf)
- OUT: Ali Ahmed (international duty)
- OUT: Andrés Cubas (international duty)
- OUT: Damir Kreilach (calf)
